Aspirin use linked to reduced aneurysm rupture risk

A new study led by the University of Iowa and the Mayo Clinic suggests that regular use of aspirin may reduce the risk for rupture of intracranial aneurysms.

If confirmed with future research, new avenues for the treatment of unruptured brain aneurysms could be opened, according to James Torner, head of epidemiology in the UI College of Public Health.

The preliminary findings, recently published in the clinical neurology journal Stroke, showed that participants who took aspirin at least three times a week had a significantly lower risk of hemorrhage compared to those who used aspirin less often or never. The study supports the theory that chronic inflammation contributes to the risk for rupture of intracranial aneurysms.

In addition to Torner, the UI research team included neurosurgeons David Hasan and Kelly Mahaney, and Ana Capuano of the College of Public Health.

The study participants were from the International Study of Unruptured Intracranial Aneurysms, a study for which Torner serves as chief neurosurgical investigator.